Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name slik
Flybase description The gene Sterile20-like kinase is referred to in FlyBase by the symbol Dmel\slik (CG4527, FBgn0035001).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.3835 2.2611 -0.439048 2.4974 -1.921071 -1.04 0.59206 -0.846639
    Affimetrix absolute value 7.942 8.785 8.055 9.68 7.895 8.505 8.832 7.786
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: positive regulation of peptidyl-threonine phosphorylation; cell proliferation; protein phosphorylation; cytokinesis; regulation of localization.
20 alleles are reported.
The phenotypes of these alleles are annotated with: 1st posterior cell; peripodial epithelium; wing.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Polo kinase kinase; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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