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Gene name | Mmp1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Matrix metalloproteinase 1 is referred to in FlyBase by the symbol Dmel\Mmp1 (CG4859, FBgn0035049). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: metalloendopeptidase activity. There is experimental evidence for 12 unique biological process terms, many of which group under: open tracheal system development; cellular component organization or biogenesis; growth; programmed cell death; developmental growth; cellular process; molting cycle, chitin-based cuticle; gland morphogenesis; biological regulation; post-embryonic organ morphogenesis; instar larval development. 31 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/larval trachea; embryonic/larval posterior spiracle; second instar larval cuticle; chaeta; embryonic/larval dorsal trunk; adult thoracic sensillum; mesothoracic tergum; third instar larva; embryonic/larval transverse connective. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: Hemopexin/matrixin; Hemopexin/matrixin, conserved site; Hemopexin/matrixin, repeat; Metallopeptidase, catalytic domain; Peptidase M10, metallopeptidase; Peptidase M10A, matrix metallopeptidase; Peptidase M10A, matrix metallopeptidase, stromelysin type; Peptidase, metallopeptidase; Peptidoglycan binding-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the pupal period. . |