Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name hipk
Flybase description The gene homeodomain interacting protein kinase is referred to in FlyBase by the symbol Dmel\hipk (CG17090, FBgn0035142).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.2552 -1.5812 -2.382686 -2.3557 -4.44976 -2.0553 -2.27351 -3.607179
    Affimetrix absolute value 7.245 6.962 6.955 7.2 6.662 7.532 7.381 6.457
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: beta-catenin binding; transcription factor binding; protein serine/threonine kinase activity; protein kinase activity.
There is experimental evidence that it is involved in the biological process: positive regulation of Wnt receptor signaling pathway; compound eye development; imaginal disc-derived wing margin morphogenesis; protein stabilization; protein phosphorylation; imaginal disc-derived wing vein morphogenesis; positive regulation of Notch signaling pathway.
34 alleles are reported.
The phenotypes of these alleles are annotated with: wing margin; eye disc; eye; intersegmental nerve; eye photoreceptor cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout the pupal period.
.