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| Gene name | Trh | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Tryptophan hydroxylase is referred to in FlyBase by the symbol Dmel\Trh (CG9122, FBgn0035187). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: phenylalanine 4-monooxygenase activity; tryptophan 5-monooxygenase activity. There is experimental evidence that it is involved in the biological process: regulation of circadian sleep/wake cycle, sleep; serotonin biosynthetic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Aromatic amino acid hydroxylase; Aromatic amino acid hydroxylase, C-terminal; Aromatic amino acid hydroxylase, iron/copper binding site; Tryptophan 5-monooxygenase; Tyrosine 3-monooxygenase-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed within 18-24 hour embryonic stages, during early larval stages. . |
