Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mad2
Flybase description The gene mad2 is referred to in FlyBase by the symbol Dmel\mad2 (CG17498, FBgn0035640).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.6343 -9.8671 -12.764595 -12.7359 -15.721566 -10.7473 -17.59053 -12.301096
    Affimetrix absolute value 4.875 4.343 4.503 4.719 4.794 5.164 4.426 4.633
    Affymetric present call in "x" number of chips 0 0 0 2 0 2 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle spindle assembly checkpoint; regulation of mitotic prometaphase; mitotic cell cycle checkpoint; cell cycle; regulation of spindle checkpoint.
11 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DNA-binding HORMA.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
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