Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name eIF4E-4
Flybase description The gene eIF4E-4 is referred to in FlyBase by the symbol Dmel\eIF4E-4 (CG10124, FBgn0035709).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.5999 -20.613 -24.522615 -27.9905 -37.187732 -39.5628 -38.47876 -25.901117
    Affimetrix absolute value 3.489 3.299 3.564 3.588 3.566 3.267 3.287 3.561
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: translation initiation factor activity; protein binding; eukaryotic initiation factor 4G binding; RNA 7-methylguanosine cap binding.
There is experimental evidence that it is involved in the biological process: translational initiation.
2 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Eukaryotic translation initiation factor 4E (eIF-4E), conserved site; Translation Initiation factor eIF- 4e; Translation Initiation factor eIF- 4e-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected.
Peak expression observed during late pupal stages, in adult male stages.
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