Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG6673
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG6673 (FBgn0035906).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 6.8261 9.2766 4.954321 2.315 2.070981 3.5418 2.24308 3.380921
    Affimetrix absolute value 11.177 10.832 10.433 9.59 9.768 10.381 9.709 9.95
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: glutathione dehydrogenase (ascorbate) activity; transferase activity, transferring sulfur-containing groups.
There is experimental evidence that it is involved in the biological process: determination of adult lifespan; response to oxidative stress.
4 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Glutathione S-transferase, omega-class; Glutathione S-transferase/chloride channel, C-terminal; Thioredoxin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, during early larval stages.
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