Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name TrpA1
Flybase description The gene Transient receptor potential A1 is referred to in FlyBase by the symbol Dmel\TrpA1 (CG5751, FBgn0035934).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -21.8297 -10.2254 -16.03586 -17.6548 -25.952516 -1.5823 -10.8558 -11.702196
    Affimetrix absolute value 3.975 4.277 4.201 4.246 4.067 7.971 5.263 4.796
    Affymetric present call in "x" number of chips 0 0 0 0 0 3 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: calcium channel activity.
There is experimental evidence that it is involved in the biological process: memory; cellular response to heat; response to heat; circadian sleep/wake cycle; thermotaxis; detection of chemical stimulus involved in sensory perception of bitter taste.
20 alleles are reported.
The phenotypes of these alleles are annotated with: mesothoracic tergum; AC thermosensory neuron.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Ion transport.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.
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