Flygut: an atlas of the Drosophila adult midgut

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Gene name PGRP-LF
Flybase description The gene Peptidoglycan recognition protein LF is referred to in FlyBase by the symbol Dmel\PGRP-LF (CG4437, FBgn0035977).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.2516 -5.0874 -13.397167 -12.8627 -16.417203 -11.371 -8.3177 -11.353644
    Affimetrix absolute value 7.244 5.298 4.438 4.741 4.722 5.075 5.499 4.803
    Affymetric present call in "x" number of chips 3 3 1 3 0 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: peptidoglycan binding.
It is reported to be involved in the biological process: innate immune response; peptidoglycan catabolic process; defense response.
5 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during early pupal stages, in adult male stages.
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