Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Mnf
Flybase description The gene forkhead domain 68A is referred to in FlyBase by the symbol Dmel\fd68A (CG11799, FBgn0036134).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.9202 -1.9767 -4.081937 -2.5727 -6.896411 -3.8646 -2.05119 -4.893216
    Affimetrix absolute value 6.862 6.636 6.199 7.037 6.048 6.617 7.573 6.054
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of transcription, DNA-dependent.
14 alleles are reported.
No phenotypic data is available.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Forkhead-associated (FHA) domain; SMAD/FHA domain; Transcription factor, fork head; Transcription factor, fork head, conserved site; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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