Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Smn
Flybase description The gene survival motor neuron is referred to in FlyBase by the symbol Dmel\Smn (CG16725, FBgn0036641).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.3324 -2.195 -2.291674 -2.3385 -2.406001 -2.8673 -3.54258 -2.359757
    Affimetrix absolute value 7.188 6.489 6.982 7.166 7.494 7.052 6.737 7.003
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: alpha-actinin binding.
There is experimental evidence that it is involved in the biological process: ribonucleoprotein complex assembly; spliceosomal snRNP assembly; neuromuscular junction development; skeletal muscle thin filament assembly.
25 alleles are reported.
The phenotypes of these alleles are annotated with: wing vein L5; dorsal medial muscle; striated muscle thin filament; posterior crossvein; NMJ bouton; wing vein L4; indirect flight muscle motor neuron; indirect flight muscle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Survival motor neuron; Tudor domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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