Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name eRF1
Flybase description The gene eukaryotic release factor 1 is referred to in FlyBase by the symbol Dmel\eRF1 (CG5605, FBgn0036974).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of eRF1 along the gutCropCardia/R1R2R3R4R5Hindgut-2-1012Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.0063 3.4892 2.391759 1.6758 1.414577 1.3954 1.86988 1.862754
    Affimetrix absolute value 9.393 9.387 9.432 9.126 9.258 9.041 9.448 9.126
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of eRF1 in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h00.511.5Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: translation termination factor activity.
There is experimental evidence that it is involved in the biological process: smoothened signaling pathway; translational termination; autophagic cell death; salivary gland cell autophagic cell death.
28 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; dorsocentral bristle; tormogen cell; scutellar bristle.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Peptide Chain Release Factor eRF1/aRF1, N-terminal; Peptide chain release factor eRF1/aRF1; eRF1 domain 1/Pelota-like; eRF1 domain 2; eRF1 domain 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.
.