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| Gene name | CG7145 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene delta-1-Pyrroline-5-carboxylate dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\P5CDh1 (CG7145, FBgn0037138). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: 1-pyrroline-5-carboxylate dehydrogenase activity. There is experimental evidence that it is involved in the biological process: proline metabolic process; mitochondrion organization. 15 alleles are reported. The phenotype of these alleles is annotated with: mitochondrion. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Aldehyde dehydrogenase domain; Aldehyde dehydrogenase, C-terminal; Aldehyde dehydrogenase, N-terminal; Aldehyde dehydrogenase, conserved site; Aldehyde/histidinol dehydrogenase; Delta-1-pyrroline-5-carboxylate dehydrogenase 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes. . |
