Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hcs
Flybase description The gene Holocarboxylase synthetase is referred to in FlyBase by the symbol Dmel\Hcs (CG14670, FBgn0037332).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of Hcs along the gutCropCardia/R1R2R3R4R5Hindgut00.511.52Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.9815 -3.5953 -5.1202 -5.819 -9.084784 -7.381 -8.01571 -8.030577
    Affimetrix absolute value 5.835 5.784 5.873 5.847 5.636 5.681 5.565 5.323
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity.
There is experimental evidence that it is involved in the biological process: response to heat.
7 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Biotin protein ligase, C-terminal; Biotin--acetyl-CoA-carboxylase ligase; Biotin/lipoate A/B protein ligase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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