Flygut: an atlas of the Drosophila adult midgut

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Gene name CG1076
Flybase description The gene Vacuolar H+ ATPase subunit 14-2 is referred to in FlyBase by the symbol Dmel\Vha14-2 (CG1076, FBgn0037402).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of CG1076 along the gutCropCardia/R1R2R3R4R5Hindgut-1.5-1-0.50Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -60.0188 -33.1931 -46.750976 -58.1854 -64.807314 -62.6225 -67.20287 -41.836669
    Affimetrix absolute value 2.511 2.601 2.681 2.543 2.745 2.598 2.486 2.863
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of CG1076 in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h-1.5-1-0.500.511.5Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: hydrogen-exporting ATPase activity, phosphorylative mechanism.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ATP hydrolysis coupled proton transport.
2 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: ATPase, V1 complex, subunit F, eukaryotic; ATPase, V1/A1 complex, subunit F.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed at stages throughout the pupal period, in adult male stages.
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