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Gene name | Sp7 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Serine protease 7 is referred to in FlyBase by the symbol Dmel\Sp7 (CG3066, FBgn0037515). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: melanization defense response; positive regulation of melanization defense response. 12 alleles are reported. The phenotype of these alleles is annotated with: melanotic mass. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Disulphide knot CLIP; Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like; Proteinase, regulatory CLIP domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during late larval stages, during early pupal stages. . |