Flygut: an atlas of the Drosophila adult midgut

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Gene name lkb1
Flybase description The gene lkb1 is referred to in FlyBase by the symbol Dmel\lkb1 (CG9374, FBgn0038167).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -15.3701 -8.1304 -6.850051 -9.685 -12.775302 -12.9547 -4.56053 -10.516392
    Affimetrix absolute value 4.467 4.6 5.409 5.13 5.085 4.87 6.362 4.862
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: protein kinase activity.
There is experimental evidence that it is involved in the biological process: border follicle cell delamination; dorsal closure; regulation of JNK cascade; oocyte microtubule cytoskeleton organization; determination of adult lifespan; pole plasm oskar mRNA localization; mitotic spindle organization; asymmetric neuroblast division; positive regulation of apoptosis.
26 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; organ system; organelle; adult segment; spindle; thoracic segment; intracellular organelle part; spindle microtubule; portion of tissue; multicellular structure.
It has 9 annotated transcripts and 9 annotated polypeptides.
Protein features are: Calcium/calmodulin-dependent/calcium-dependent protein kinase; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-11; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.
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