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| Gene name | twf | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene twinfilin is referred to in FlyBase by the symbol Dmel\twf (CG3172, FBgn0038206). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process: neuromuscular synaptic transmission; regulation of lamellipodium assembly; border follicle cell migration; synaptic vesicle endocytosis; actin filament depolymerization; bristle morphogenesis; mushroom body development. 7 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system subdivision; organ system; multicellular structure; sense organ; adult segment; adult; external compound sense organ; peripheral nervous system; organelle; protocerebrum; actin cytoskeleton; acellular anatomical structure. It has one annotated transcript and one annotated polypeptide. Protein features are: Actin-binding, cofilin/tropomyosin type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. . |
