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Gene name | Gyc88E | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Guanylyl cyclase at 88E is referred to in FlyBase by the symbol Dmel\Gyc88E (CG4154, FBgn0038295). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: guanylate cyclase activity; carbon monoxide binding; oxygen sensor activity; oxygen binding; heme binding; protein homodimerization activity; nitric oxide binding. There is experimental evidence that it is involved in the biological process: response to hypoxia; cGMP biosynthetic process. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Haem NO binding associated; Heme-NO binding; NO signalling/Golgi transport ligand-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages. . |