Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Prx5
Flybase description The gene Peroxiredoxin 5 is referred to in FlyBase by the symbol Dmel\Prx5 (CG7217, FBgn0038570).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 6.2098 4.1394 2.790922 3.3246 2.058216 2.7417 6.79188 2.993764
    Affimetrix absolute value 11.038 9.658 9.634 10.116 9.787 10.016 11.313 9.771
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: antioxidant activity.
There is experimental evidence that it is involved in the biological process: cell redox homeostasis; determination of adult lifespan; negative regulation of apoptosis; response to oxidative stress.
4 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Redoxin; Thioredoxin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.
The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.
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