Flygut: an atlas of the Drosophila adult midgut

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Gene name sar1
Flybase description The gene sar1 is referred to in FlyBase by the symbol Dmel\sar1 (CG7073, FBgn0038947).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 6.8465 10.4932 6.049274 4.547 3.451112 4.4245 3.56779 5.378885
    Affimetrix absolute value 11.176 10.994 10.752 10.568 10.54 10.701 10.384 10.618
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity; GTP binding.
There is experimental evidence that it is involved in the biological process: chitin-based cuticle development; chitin-based larval cuticle pattern formation; endoplasmic reticulum organization; negative regulation of dendrite morphogenesis; positive regulation of cuticle pigmentation; larval chitin-based cuticle development; embryonic heart tube development.
12 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; sarcomere; cardioblast; embryonic pericardial cell; embryonic/larval epidermis.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily, ARF/SAR type; Small GTPase superfamily, SAR1-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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