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| Gene name | Dcr-1 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Dicer-1 is referred to in FlyBase by the symbol Dmel\Dcr-1 (CG4792, FBgn0039016). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; bidentate ribonuclease III activity. There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; gene silencing; gene expression; multicellular organism reproduction; multicellular organismal development; gene silencing by miRNA; gamete generation; dsRNA fragmentation; RNA interference. 22 alleles are reported. The phenotypes of these alleles are annotated with: oocyte; embryonic/larval neuromuscular junction. It has one annotated transcript and one annotated polypeptide. Protein features are: Argonaute/Dicer protein, PAZ; Dicer double-stranded RNA-binding fold; Double-stranded RNA-binding; Helicase, C-terminal; Ribonuclease III. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |
