Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name p53
Flybase description The gene p53 is referred to in FlyBase by the symbol Dmel\p53 (CG33336, FBgn0039044).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.5072 -1.4467 -0.770928 -3.2656 -2.222462 -1.5706 -3.08004 -1.94884
    Affimetrix absolute value 7.093 7.118 7.729 6.748 7.627 7.924 6.937 7.306
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 18 unique biological process terms, many of which group under: biological regulation; programmed cell death; regulation of apoptosis; cell death; response to abiotic stimulus; localization; response to ionizing radiation; response to UV; determination of adult lifespan; growth; cell cycle.
49 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye; interommatidial bristle; ovary; pole cell; germline cell; wing; outer photoreceptor cell; egg chamber; ommatidium.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: p53 tumour suppressor family; p53, DNA-binding domain; p53-like transcription factor, DNA-binding; p53/RUNT-type transcription factor, DNA-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
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