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Gene name | p53 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene p53 is referred to in FlyBase by the symbol Dmel\p53 (CG33336, FBgn0039044). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence for 18 unique biological process terms, many of which group under: biological regulation; programmed cell death; regulation of apoptosis; cell death; response to abiotic stimulus; localization; response to ionizing radiation; response to UV; determination of adult lifespan; growth; cell cycle. 49 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; interommatidial bristle; ovary; pole cell; germline cell; wing; outer photoreceptor cell; egg chamber; ommatidium. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: p53 tumour suppressor family; p53, DNA-binding domain; p53-like transcription factor, DNA-binding; p53/RUNT-type transcription factor, DNA-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |