Flygut: an atlas of the Drosophila adult midgut

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Gene name Irk2
Flybase description The gene Inwardly rectifying potassium channel 2 is referred to in FlyBase by the symbol Dmel\Irk2 (CG4370, FBgn0039081).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 5.1662 1.8036 -3.520227 -16.8316 -20.930802 -6.3515 19.78348 0.711361
    Affimetrix absolute value 10.768 8.452 6.37 4.35 4.4 6.044 12.842 8.654
    Affymetric present call in "x" number of chips 3 3 3 3 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: inward rectifier potassium channel activity.
There is experimental evidence that it is involved in the biological process: potassium ion transport; regulation of membrane potential.
5 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Immunoglobulin E-set; Potassium channel, inwardly rectifying, Kir; Potassium channel, inwardly rectifying, Kir, conserved region 2; Potassium channel, inwardly rectifying, Kir, cytoplasmic; Potassium channel, inwardly rectifying, Kir-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages.
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