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Gene name | Miro | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Mitochondrial Rho is referred to in FlyBase by the symbol Dmel\Miro (CG5410, FBgn0039140). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: GTP binding; calcium ion binding; GTPase activity. There is experimental evidence that it is involved in the biological process: synaptic transmission; mitochondrion localization; synaptic vesicle transport; establishment of mitochondrion localization, microtubule-mediated; microtubule cytoskeleton organization; cytoplasmic microtubule organization. 13 alleles are reported. The phenotypes of these alleles are annotated with: neuron; dendrite; dorsal multidendritic neuron ddaE; mitochondrion. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Calcium-binding EF-hand; EF hand associated, type-1; EF hand associated, type-2; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand-like domain; MIRO; Mitochondrial Rho-like; Small GTPase superfamily; Small GTPase superfamily, mitochondrial rho type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages, in adult male stages. . |