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Gene name | spas | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene spastin is referred to in FlyBase by the symbol Dmel\spas (CG5977, FBgn0039141). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ATPase activity. There is experimental evidence that it is involved in the biological process: locomotory behavior; hemocyte migration; microtubule cytoskeleton organization; positive regulation of microtubule depolymerization. 28 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; peripheral nervous system; organelle; multicellular structure; intracellular non-membrane-bounded organelle; cell part; intracellular organelle part; intracellular organelle; cytoplasmic part; multidendritic neuron; adult segment. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: ATPase, AAA+ type, core; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; MIT. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in adult female stages. . |