Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name atl
Flybase description The gene atlastin is referred to in FlyBase by the symbol Dmel\atl (CG6668, FBgn0039213).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 5.1441 7.7148 4.902721 2.1168 3.00147 3.0583 1.54053 3.491664
    Affimetrix absolute value 10.75 10.562 10.458 9.454 10.337 10.17 9.167 10.009
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: guanyl ribonucleotide binding; protein homodimerization activity; GTPase activity.
There is experimental evidence that it is involved in the biological process: membrane fusion; endoplasmic reticulum membrane fusion; regulation of microtubule depolymerization; neuromuscular junction development; regulation of synaptic growth at neuromuscular junction.
20 alleles are reported.
The phenotypes of these alleles are annotated with: NMJ bouton; oocyte; postsynaptic membrane; dopaminergic neuron; abdominal 2 ventral longitudinal muscle 4; endoplasmic reticulum; embryonic/larval somatic muscle; abdominal 2 ventral longitudinal muscle 3.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Guanylate-binding protein, C-terminal; Guanylate-binding protein, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult male stages.
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