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Gene name | polybromo | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene polybromo is referred to in FlyBase by the symbol Dmel\polybromo (CG11375, FBgn0039227). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding. There is experimental evidence that it is involved in the biological process: eggshell chorion assembly; negative regulation of chromatin silencing; vitelline membrane formation involved in chorion-containing eggshell formation; imaginal disc-derived leg morphogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with: chorion; vitelline membrane. It has one annotated transcript and one annotated polypeptide. Protein features are: Bromo adjacent homology (BAH) domain; Bromodomain; Bromodomain, conserved site; High mobility group, HMG1/HMG2; High mobility group, superfamily; Zinc finger, C2H2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. . |