Flygut: an atlas of the Drosophila adult midgut

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Gene name CG5959
Flybase description The gene multicopper oxidase 3 is referred to in FlyBase by the symbol Dmel\MCO3 (CG5959, FBgn0039387).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of CG5959 along the gutCropCardia/R1R2R3R4R5Hindgut-1.5-1-0.50Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -48.3847 -28.1373 -40.975536 -46.0127 -65.818297 -56.0314 -54.75807 -39.852101
    Affimetrix absolute value 2.843 2.814 2.872 2.87 2.723 2.757 2.776 2.952
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of CG5959 in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h-2-1012Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: L-ascorbate oxidase activity; iron ion transmembrane transporter activity; ferroxidase activity.
There is experimental evidence that it is involved in the biological process: copper ion homeostasis.
2 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cupredoxin; Multicopper oxidase, copper-binding site; Multicopper oxidase, type 1; Multicopper oxidase, type 2; Multicopper oxidase, type 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected.
Peak expression observed during late pupal stages.
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