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Gene name | Mtl | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Mig-2-like is referred to in FlyBase by the symbol Dmel\Mtl (CG5588, FBgn0039532). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity. There is experimental evidence that it is involved in the biological process: dorsal closure, elongation of leading edge cells; dorsal closure; actin filament bundle assembly; response to DNA damage stimulus; JNK cascade; hemocyte migration; germ-band shortening; head involution; lamellipodium assembly; salivary gland morphogenesis. 14 alleles are reported. The phenotypes of these alleles are annotated with: presumptive embryonic salivary gland; adult mushroom body; longitudinal connective. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rho type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages. . |