Flygut: an atlas of the Drosophila adult midgut

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Gene name PH4alphaNE1
Flybase description The gene prolyl-4-hydroxylase-alpha NE1 is referred to in FlyBase by the symbol Dmel\PH4αNE1 (CG9728, FBgn0039780).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.9015 -11.5317 -17.078302 -21.6402 -27.155301 -24.9822 -24.50269 -18.812731
    Affimetrix absolute value 4.723 4.187 4.182 3.959 4.04 3.925 3.936 4.008
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: procollagen-proline 4-dioxygenase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: peptidyl-proline hydroxylation to 4-hydroxy-L-proline.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Oxoglutarate/iron-dependent oxygenase; Prolyl 4-hydroxylase alpha-subunit, N-terminal; Prolyl 4-hydroxylase, alpha subunit; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed during early larval stages.
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