Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hcf
Flybase description The gene Host cell factor is referred to in FlyBase by the symbol Dmel\Hcf (CG1710, FBgn0039904).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -45.7285 -31.3724 -38.26655 -47.4737 -52.175197 -49.9765 -58.35789 -48.480186
    Affimetrix absolute value 2.911 2.663 2.929 2.819 3.053 2.919 2.685 2.659
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: positive regulation of growth; regulation of histone acetylation; positive regulation of transcription, DNA-dependent.
8 alleles are reported.
No phenotypic data is available.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin-like fold; Kelch repeat type 1; Kelch-type beta propeller.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.
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