Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name lgs
Flybase description The gene legless is referred to in FlyBase by the symbol Dmel\lgs (CG2041, FBgn0039907).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.9016 -0.5602 -2.695064 -2.4061 -4.775817 -2.8352 -1.8167 -3.533335
    Affimetrix absolute value 6.891 7.352 6.753 7.129 6.528 7.058 7.726 6.552
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; beta-catenin binding.
There is experimental evidence that it is involved in the biological process: positive regulation of Wnt receptor signaling pathway; regulation of Wnt receptor signaling pathway; imaginal disc-derived wing margin morphogenesis; Wnt receptor signaling pathway; segment polarity determination.
20 alleles are reported.
The phenotypes of these alleles are annotated with: wing margin; embryonic/first instar larval cuticle; leg; antenna; sternite; wing; imaginal disc.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
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