Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name klhl10
Flybase description This gene is referred to in FlyBase by the symbol Dmel\klhl10 (CG12423, FBgn0040038).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -59.2596 -34.8449 -50.096841 -59.2183 -70.889549 -71.2712 -65.44693 -52.391056
    Affimetrix absolute value 2.536 2.513 2.591 2.509 2.621 2.416 2.529 2.563
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; heme binding; electron carrier activity.
There is experimental evidence that it is involved in the biological process: activation of caspase activity; sperm individualization; protein ubiquitination.
12 alleles are reported.
The phenotypes of these alleles are annotated with: eye; spermatid; ommatidium.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: BTB/Kelch-associated; BTB/POZ; BTB/POZ fold; BTB/POZ-like; Cytochrome P450; Kelch-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed in adult male stages.
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