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Gene name | pont | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene pontin is referred to in FlyBase by the symbol Dmel\pont (CG4003, FBgn0040078). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: beta-catenin binding; TBP-class protein binding; DNA helicase activity. There is experimental evidence that it is involved in the biological process: positive regulation of gene expression; spindle assembly involved in mitosis; mitotic cell cycle G2/M transition DNA damage checkpoint. 11 alleles are reported. The phenotype of these alleles is annotated with: wing. It has one annotated transcript and one annotated polypeptide. Protein features are: ATPase, AAA+ type, core; Nucleic acid-binding, OB-fold-like; TIP49, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. . |