Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name krz
Flybase description The gene kurtz is referred to in FlyBase by the symbol Dmel\krz (CG1487, FBgn0040206).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.5234 -4.8155 -8.406373 -9.4694 -18.894254 -13.0116 -8.48693 -11.844074
    Affimetrix absolute value 6.633 5.376 5.113 5.149 4.537 4.862 5.5 4.713
    Affymetric present call in "x" number of chips 3 3 3 3 0 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: negative regulation of Notch signaling pathway; instar larval development; locomotory exploration behavior; regulation of protein stability; negative regulation of protein tyrosine kinase activity; gastrulation; cuticle development.
29 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; 1st posterior cell; lamellocyte; wing blade; embryonic/larval fat body; wing vein.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Arrestin; Arrestin, C-terminal; Arrestin, N-terminal; Arrestin, conserved site; Arrestin-like, C-terminal; Arrestin-like, N-terminal; Immunoglobulin E-set.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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