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| Gene name | Best1 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Bestrophin 1 is referred to in FlyBase by the symbol Dmel\Best1 (CG6264, FBgn0040238). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: chloride channel activity; volume-sensitive chloride channel activity. There is experimental evidence that it is involved in the biological process: chloride transport; cell volume homeostasis. 15 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Bestrophin; Bestrophin/UPF0187. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult female stages. . |
