Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name robo3
Flybase description The gene robo3 is referred to in FlyBase by the symbol Dmel\robo3 (CG5423, FBgn0041097).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -26.0122 -12.5244 -20.477155 -26.8519 -28.128152 -33.7841 -30.16421 -20.374556
    Affimetrix absolute value 3.722 4.008 3.83 3.647 3.967 3.492 3.637 3.949
    Affymetric present call in "x" number of chips 0 1 0 1 0 0 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: axon guidance receptor activity.
There is experimental evidence that it is involved in the biological process: axon guidance; gonad development; mushroom body development; ventral cord development; neuron recognition; central complex development.
25 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; organ system; adult segment; adult; external compound sense organ; peripheral nervous system; embryonic/larval neuron; longitudinal connective; histaminergic neuron; multidendritic neuron.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages.
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