Flygut: an atlas of the Drosophila adult midgut

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Gene name park
Flybase description The gene parkin is referred to in FlyBase by the symbol Dmel\park (CG10523, FBgn0041100).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.4964 -7.4509 -11.313751 -6.2073 -11.183156 -11.0716 -7.5444 -9.802856
    Affimetrix absolute value 5.505 4.725 4.703 5.763 5.283 5.103 5.649 4.996
    Affymetric present call in "x" number of chips 3 2 1 3 3 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ubiquitin conjugating enzyme binding; ubiquitin-protein ligase activity.
There is experimental evidence that it is involved in the biological process: protein autoubiquitination; mitochondrial fission; sperm mitochondrion organization; response to oxidative stress; negative regulation of JNK cascade; oogenesis; regulation of mitochondrion organization; mitochondrion organization; protein ubiquitination; spermatogenesis.
36 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system; multicellular structure; cytoplasmic part; anatomical structure; organelle; elongation stage spermatid; organ system subdivision; adult; adult segment; intracellular organelle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Parkin; Ubiquitin; Ubiquitin subgroup; Ubiquitin supergroup; Zinc finger, C6HC-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed in adult male stages.
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