| Home | Overview of gut regions | Anatomy | Histology | Transgene expression mapping | Gene expression |
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| Gene name | ago | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene archipelago is referred to in FlyBase by the symbol Dmel\ago (CG15010, FBgn0041171). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process: negative regulation of growth; negative regulation of glial cell proliferation; axon guidance; regulation of mitosis; DNA endoreduplication. 42 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: F-box domain, Skp2-like; F-box domain, cyclin-like; G-protein beta WD-40 repeat; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. . |
