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Gene name | TepI | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Thiolester containing protein I is referred to in FlyBase by the symbol Dmel\TepI (CG18096, FBgn0041183). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: endopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process: antibacterial humoral response. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: A-macroglobulin complement component; Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin, receptor-binding; Terpenoid cylases/protein prenyltransferase alpha-alpha toroid. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed during late larval stages, during early pupal stages. . |