Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Socs36E
Flybase description The gene Suppressor of cytokine signaling at 36E is referred to in FlyBase by the symbol Dmel\Socs36E (CG15154, FBgn0041184).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.2861 4.503 4.15889 2.3675 2.924005 3.4955 -2.77491 4.547592
    Affimetrix absolute value 8.08 9.699 10.141 9.559 10.227 10.22 7.148 10.37
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: notum morphogenesis; germ-line stem cell maintenance; negative regulation of sevenless signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of epidermal growth factor receptor signaling pathway; haltere development; compound eye pigmentation; imaginal disc-derived wing vein morphogenesis; negative regulation of R7 cell differentiation; long-term memory.
21 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor cell R7; eye; male germline stem cell; anterior crossvein; haltere; border follicle cell; wing; humerus; wing vein; pigment cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: SH2 motif; SOCS protein, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 06-12 hour embryonic stages.
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