Flygut: an atlas of the Drosophila adult midgut

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Gene name Cct1
Flybase description The gene CTP:phosphocholine cytidylyltransferase 1 is referred to in FlyBase by the symbol Dmel\Cct1 (CG1049, FBgn0041342).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5317 2.3517 -1.793425 -1.39 -1.854672 -1.3507 -2.41598 -1.408311
    Affimetrix absolute value 7.794 8.845 7.34 7.922 7.874 8.136 7.318 7.801
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: choline-phosphate cytidylyltransferase activity.
There is experimental evidence that it is involved in the biological process: eye development; endocytosis; determination of adult lifespan; oogenesis; imaginal disc-derived wing morphogenesis; establishment of ommatidial planar polarity.
39 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; multicellular structure; cytoplasmic part; external compound sense organ; ovariole; cell part; organ system subdivision; peripheral nervous system; endomembrane system; multi-tissue structure.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Cytidyltransferase-related; Cytidylyltransferase; Rossmann-like alpha/beta/alpha sandwich fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 12-18 embryonic stages, in stages of adults of both sexes.
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