Flygut: an atlas of the Drosophila adult midgut

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Gene name Ku80
Flybase description The gene Ku80 is referred to in FlyBase by the symbol Dmel\Ku80 (CG18801, FBgn0041627).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.9866 -4.9374 -6.337597 -5.9604 -6.559252 -6.6985 -14.47107 -6.970144
    Affimetrix absolute value 4.957 5.333 5.558 5.823 6.056 5.865 4.715 5.45
    Affymetric present call in "x" number of chips 1 2 1 3 3 3 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATP-dependent DNA helicase activity; single-stranded DNA-dependent ATP-dependent DNA helicase activity.
There is experimental evidence that it is involved in the biological process: telomere maintenance.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DNA helicase, ATP-dependent, Ku type; DNA helicase, ATP-dependent, Ku80 subunit; Ku, C-terminal; Ku70/Ku80 C-terminal arm; Ku70/Ku80, N-terminal alpha/beta; Spen Paralogue and Orthologue SPOC, C-terminal-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.
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