Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name NfI
Flybase description The gene Nuclear factor I is referred to in FlyBase by the symbol Dmel\NfI (CG2380, FBgn0042696).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -39.2697 -33.7188 -62.513832 -64.7222 -78.802658 -67.2766 -48.59695 -55.82756
    Affimetrix absolute value 3.144 2.601 2.223 2.389 2.466 2.492 2.953 2.483
    Affymetric present call in "x" number of chips 2 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of transcription, DNA-dependent; DNA replication.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: CTF transcription factor/nuclear factor 1; CTF transcription factor/nuclear factor 1, DNA-binding domain; CTF transcription factor/nuclear factor 1, N-terminal; MAD homology 1, Dwarfin-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.
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