Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cbt
Flybase description The gene cabut is referred to in FlyBase by the symbol Dmel\cbt (CG4427, FBgn0043364).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.5218 4.9104 2.855601 2.8982 1.853028 2.38 2.57823 2.314023
    Affimetrix absolute value 10.207 9.9 9.626 9.916 9.582 9.808 9.906 9.349
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding.
There is experimental evidence that it is involved in the biological process: dorsal closure; sensory organ development; wing disc dorsal/ventral pattern formation; autophagic cell death; salivary gland cell autophagic cell death.
9 alleles are reported.
The phenotypes of these alleles are annotated with: dorsal closure embryo; trichogen cell; dorsocentral bristle; amnioserosa; ocellus; tormogen cell; scutellar bristle; embryonic leading edge cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 18-24 hour embryonic stages.
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