Flygut: an atlas of the Drosophila adult midgut

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Gene name CG4747
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG4747 (FBgn0043456).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.3347 -1.1732 -2.006996 -1.9389 -3.386828 -2.0073 -2.48817 -2.55412
    Affimetrix absolute value 6.713 7.392 7.201 7.46 7.032 7.56 7.251 6.953
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 3-hydroxyisobutyrate dehydrogenase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: pentose-phosphate shunt.
5 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; dorsocentral bristle; tormogen cell; scutellar bristle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: 3-hydroxyacid dehydrogenase/reductase; 6-phosphogluconate dehydrogenase, C-terminal-like; 6-phosphogluconate dehydrogenase, NADP-binding; Dehydrogenase, multihelical; NAD(P)-binding domain; PWWP.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages.
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