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Gene name | Pak3 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Pak3 is referred to in FlyBase by the symbol Dmel\Pak3 (CG14895, FBgn0044826). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: receptor signaling protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process: actin filament organization. 17 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; embryonic/larval cuticle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: PAK-box/P21-Rho-binding; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. . |