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Gene name | Stim | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Stromal interaction molecule is referred to in FlyBase by the symbol Dmel\Stim (CG9126, FBgn0045073). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: calcium-induced calcium release activity; store-operated calcium channel activity. There is experimental evidence that it is involved in the biological process: bristle development; positive regulation of calcium ion transport via store-operated calcium channel activity; positive regulation of NFAT protein import into nucleus; activation of store-operated calcium channel activity; imaginal disc-derived wing morphogenesis. 12 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; adult segment; organ system; thoracic segment; external compound sense organ; adult; embryonic/larval fat body; embryo-derived cell-line; imaginal precursor; cultured cell-line; wing margin bristle; integumentary plate; peripheral nervous system. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: EF-hand-like domain; Sterile alpha motif domain; Sterile alpha motif homology; Sterile alpha motif, type 2; Sterile alpha motif-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. . |