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| Gene name | Gclm | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Glutamate-cysteine ligase modifier subunit is referred to in FlyBase by the symbol Dmel\Gclm (CG4919, FBgn0046114). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: glutamate-cysteine ligase catalytic subunit binding; enzyme binding; enzyme regulator activity. There is experimental evidence that it is involved in the biological process: olfactory learning; learning or memory; glutathione biosynthetic process; response to DNA damage stimulus; positive regulation of glutamate-cysteine ligase activity. 13 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: NADP-dependent oxidoreductase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages, during early larval stages, in adult female stages. . |
